Process for producing kampo medicine hard capsules
US5318798A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 8, 1992 |
| Grant date | Jun 7, 1994 |
| Priority date | — |
| Expiry date | Sep 8, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K36/9066
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
When a powdered extract of Kampo medicine is encapsulated as such in hard capsules, the pharmaceutical effects of the Kampo medicine cannot be fully achieved, since the dissolution of the content of the hard capsules requires a long period of time. Therefore, the present invention aims at providing Kampo medicine hard capsules having good dissolution properties. The present invention provides a process for producing Kampo medicine hard capsules which comprises compacting Kampo medicine extract powder, mixing magnesium stearate with the compacted Kampo medicine extract powder and filing the mixture into gelatin hard capsules. It is preferable that the weight ratio of the magnesium stearate to the Kampo medicine powdered extract ranges from 0.5/100 to 3/100. Furthermore, it is preferable that said Kampo medicine is selected from Oren-gedoku-to, Sho-saiko-to, Ninjin-to, San'o-shashin-to, Mao-bushi-saishin-to, Anchu-san, Keishi-bukuryo-gan, Byakko-ka-ninjin-to, Shakuyaku-kanzo-to and Sairei-to.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.