Enhanced gene expression in response to lactation signals
US5320952A · kind A · utility
13Cited by
4References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 2, 1993 |
| Grant date | Jun 14, 1994 |
| Priority date | — |
| Expiry date | Jun 2, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/85
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
An expression method for enhanced recombinant production of a desired protein due to the presence of lactation-signals is provided which comprises cells transformed with a DNA sequence having the desired protein coding sequence under the control of a bovine prolactin promoter and a bovine prolactin distal enhancer sequence. A preferred embodiment uses growth hormone sequences as the desired protein coding sequences. In this embodiment, feed-efficiency of milk-producing animals is improved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.