4-methylthiazole derivatives, their methods of preparation and the pharmaceutical compositions in which they are present
US5322846A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 19, 1992 |
| Grant date | Jun 21, 1994 |
| Priority date | — |
| Expiry date | Oct 19, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel 4-methylthiazole derivatives, to tr methods of preparation and to the pharmaceutical compositions in which they are present. According to the invention, these derivatives have the general formula ##STR1## in which n is equal to 0 or 1 and R.sub.1 and R.sub.2, which are identical or different, are selected from a hydrogen atom, a halogen, a hydroxyl group, a trifluoromethyl group, an alkyl group having from 1 to 4 carbon atoms and an alkoxy group having from 1 to 5 carbon atoms and are useful in the treatment of cardiovascular diseases associated with hyperactivity of the sympathetic nervous system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.