Indole derivatives
US5322851A · kind A · utility
7Cited by
7References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 25, 1993 |
| Grant date | Jun 21, 1994 |
| Priority date | — |
| Expiry date | Feb 25, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D413/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Specific 2- and 2,5-substituted indoles or 2,3-dihydroindole compounds of the following formula ##STR1## wherein, R is formula 1a ##STR2## and X, X', Ar, R.sup.1, n, U, Z, V and W are defined in the specification are provided, having long lasting serotonin activity with specific binding to 5-HT.sub.2 receptors of the central nervous system. These compounds are suitable for therapeutic treatment of CNS disorders, such as anxiety, depression, sleep disturbances, migraine, negative symptoms of schizophrenia, and Parkinson's disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.