Cholesterol lowering compounds
US5322855A · kind A · utility
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4References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 24, 1992 |
| Grant date | Jun 21, 1994 |
| Priority date | — |
| Expiry date | Nov 24, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D493/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Zaragozic acids isolated from a culture of MF5465 have been subjected to photoreaction, then derivatized at the 4-keto position. The resulting derivatives are active as squalene synthetase inhibitors and are useful in the treatment of hypercholesterolemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.