Radiopharmaceuticals for imaging the heart
US5324502A · kind A · utility
21Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 2, 1992 |
| Grant date | Jun 28, 1994 |
| Priority date | — |
| Expiry date | Apr 2, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Radiopharmaceuticals for imaging myocardial tissues are prepared by forming lipophilic, cationic complexes of radioactive metal ions with metal chelating ligands comprising the Schiff base adducts of triamines and tetraamines with optionally substituted salicylaldehydes. The lipophilic, cationic, radioactive complexes of the invention exhibit high uptake and retention in myocardial tissues. Preferred gallium-68(III) complexes in accordance with this invention can be used to image the heart using positron emission tomography.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.