Method and device for improved restriction fragment length polymorphism analysis
US5324631A · kind A · utility
30Cited by
5References
9Claims
0Family size
Inventors
Key dates
| Filing date | Aug 26, 1991 |
| Grant date | Jun 28, 1994 |
| Priority date | — |
| Expiry date | Aug 26, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/683
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Improvements in the efficiency and sensitivity of restriction fragment length polymorphism (RFLP) detection in target sequences are realized by developing primers that are specific for nucleic acid sequences, labelling those primers with distinguishable, non-radioactive labels, such as chromophores, and applying the primers in sets such that, after amplification of the target sequence, specific sequences, in particular those of RFLPs, can be identified by virtue of the probe(s) which hybridized.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.