Acid-labile subunit (ALS) of insulin-like growth factor binding protein complex
US5324820A · kind A · utility
30Cited by
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18Claims
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Key dates
| Filing date | Dec 11, 1992 |
| Grant date | Jun 28, 1994 |
| Priority date | — |
| Expiry date | Dec 11, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/255
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An acid-labile protein is described that, when incubated with the 53-Kd acid-stable protein occupied by IGF, converts it to a high molecular weight complex, corresponding to the in vivo form of IGF. This protein is called the acid-labile subunit (ALS) of IGF binding protein complex and is provided in biologically pure form. ALS is useful in treating wounds and promoting cellular growth.
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