Formulations for nanoparticulate x-ray blood pool contrast agents using high molecular weight nonionic surfactants
US5326552A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 17, 1992 |
| Grant date | Jul 5, 1994 |
| Priority date | — |
| Expiry date | Dec 17, 2012 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to a composition comprised of nanoparticles containing an X-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith. The present invention is still further directed to a method for diagnostic imaging for use in medical procedures comprising administering to the body of a test subject in need of an X-ray an effective contrast producing amount of a composition comprised of nanoparticles containing an X-ray diagnostic compound, having a high molecular weight nonionic surfactant as a surface modifier adsorbed on the surface thereof and a cloud point modifier associated therewith.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.