Composition and device for urinary protein assay and method of using the same
US5326707A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 29, 1991 |
| Grant date | Jul 5, 1994 |
| Priority date | — |
| Expiry date | Nov 29, 2011 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6839
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A composition, test device and method of determining the presence or concentration of proteins, such as albumin, in a liquid test sample, such as urine. The test device includes a test pad with a carrier matrix incorporating a indicator reagent composition capable of interacting with proteins to produce a detectable response. The indicator reagent composition includes an indicator dye that is capable of interacting with albumin and undergoing a detectable color transition; a buffer; a hydrophobic polymeric compound having the general structural formula: ##STR1## wherein A is ##STR2## and PO is an oxypropylene unit, EO is an oxyethylene unit, y is a number in the range of 0 to about 20, z is a number in the range of 0 to about 20, the sum y+z is a number in the range of about 2 to about 20, and R.sub.2 and R.sub.3 are selected, independently, from the group consisting of hydrogen, an alkyl group, an aralkyl group, and an aryl group; R.sub.1 is either methylene or oxygen; n is a number in the range of one to about 8; and E is hydrogen or methylol when R.sub.1 is methylene, or E is hydroxy when R.sub.1 is oxygen; and a suitable carrier which is water. The indicator reagent composition…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.