Bifunctional isothiocyanate derived thiocarbonyls as ligands for metal binding
US5326856A · kind A · utility
123Cited by
11References
45Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 1992 |
| Grant date | Jul 5, 1994 |
| Priority date | — |
| Expiry date | Apr 9, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to chelating agents useful for coupling metal ions to biologically active molecules. In particular, isothiocyanate derived thiocarbonyls for chelating metals such as technetium are provided that can be conjugated to a targeting molecule such as an antibody, a peptide or a protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.