Rehydratable product and method of preparation thereof
US5328455A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 29, 1993 |
| Grant date | Jul 12, 1994 |
| Priority date | — |
| Expiry date | Mar 29, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/0448
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A hydratable iontophoretic bioelectrode including a plurality of layers of material capable of absorbing and holding an ionized fluid when placed in contact with the fluid. In one embodiment, a layer of a highly crosslinked dry hydrogel is used with a second layer of a more lightly crosslinked dry hydrogel. When the lightly crosslinked hydrogel layer is located so as to be in contact with the skin during iontophoresis, the medicament ions will be concentrated next to the skin. When the more highly crosslinked layer is located next to the conductive member, the undesirable effects of hydrolysis or corrosion of the conductive member are lessened. In another embodiment, adjacent layers are maintained at least partially out of contact from one another so as to improve the rate of hydration by disposition between the layers of spacing elements such as sugar or other dissolvable particles or cellulose or by forming a three dimensional pattern thereon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.