Use of pyrimidine 3-oxide derivatives for slowing down hair loss and topical compositions used
US5328914A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 19, 1993 |
| Grant date | Jul 12, 1994 |
| Priority date | — |
| Expiry date | Jan 19, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D239/42
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pyrimidine 3-oxide derivatives and their use for the treatment of hair loss. The compositions contain in a physiologically acceptable medium at least one compound corresponding to the formula (I): ##STR1## in which: R.sub.1 denotes a methyl or NHR.sub.4 group in which R.sub.4 denotes a C.sub.1 -C.sub.4 alkyl group or hydrogen; PA1 R.sub.2 denotes hydrogen or a group NHR.sub.4 in which R.sub.4 has the same meaning as above; R.sub.2 may also denote methyl when R.sub.1 denotes methyl; when R.sub.1 denotes NH.sub.2, R.sub.2 cannot be hydrogen; PA1 R.sub.3 may denote a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group which may optionally carry; PA2 a group OR.sub.5 in which R.sub.5 denotes a C.sub.1 -C.sub.4 alkyl group, PA2 a benzene nucleus which is optionally substituted by one or more C.sub.1 -C.sub.4 alkoxy groups; PA2 R.sub.3 may also denote a halogen atom or a nitro or amino group; PA2 and the physiologically acceptable acid addition salts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.