Recombinant streptavidin-protein chimeras useful for conjugation of molecules in the immune system
US5328985A · kind A · utility
98Cited by
5References
1Claims
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Key dates
| Filing date | Jul 12, 1991 |
| Grant date | Jul 12, 1994 |
| Priority date | — |
| Expiry date | Jul 12, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel recombinant streptavidin-protein A chimeric protein which allows conjugation of antibody molecules with biological materials. The chimeric protein is efficiently expressed in Escherichia coli and is purified by simple procedures. The purified chimetic protein can bind one biotin molecule and one to two immunoglobulin molecules per subunit.
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