Processes for making proteins having anticoagulant properties
US5328997A · kind A · utility
4Cited by
2References
4Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 28, 1993 |
| Grant date | Jul 12, 1994 |
| Priority date | — |
| Expiry date | Apr 28, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Proteins which specifically inhibit coagulation Factor Xa. The inhibitors, which do not inhibit Factor VIIa, kallikrein, trypsin, chymotrypsin, thrombin, urokinase, tissue plasminogen activator, plasmin, elastase, Factor XIa or S. aureus V8 protease, are polypeptides of 60 amino acid residues. The inhibitors may be purified from Ornithodoros moubata extract, synthesized, or produced using a recombinant DNA yeast expression system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.