Patent · US Expired

Antipyretic and analgesic methods and compositions containing optically pure R(-) ketoprofen

US5331000A · kind A · utility

40Cited by

8References

14Claims

0Family size

Assignee

Sepracor, Inc. · US

Inventors

James W. Young · Palo Alto, US
Nancy M. Gray · Ellisville, US
William J. Wechter · Redlands, US

Key dates

Filing date	Mar 1, 1993
Grant date	Jul 19, 1994
Priority date	—
Expiry date	Mar 1, 2013

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P29/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods and compositions are disclosed utilizing optically pure R(-) ketoprofen for the treatment of pain including, but not limited to, pain associated with toothaches, headaches, sprains, joint pain and post-surgical pain, for example dental pain and ophthalmic pain, while substantially reducing adverse effects including, but not limited to, gastrointestinal, renal and hepatic toxicities, and leukopenia, which are associated with the administration of racemic ketoprofen. Optically pure R(-) ketoprofen is also useful in treating pyrexia while substantially reducing the adverse effects associated with the administration of racemic ketoprofen.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.