Process for monohydroxylation of phenolic compounds
US5331103A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 26, 1993 |
| Grant date | Jul 19, 1994 |
| Priority date | — |
| Expiry date | Feb 26, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C37/60
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process for monohydroxylation of phenolic compounds which allows an increase in the amount of para isomer. The invention relates to a process for monohydroxylation of a phenolic compound having a hydrogen atom in the para position to the hydroxyl group, for the purpose of obtaining a dihydroxylated aromatic compound by reacting the initial phenolic compound with hydrogen peroxide in the presence of an effective amount of a strong acid and of a ketonic compound, said process being characterized by the fact that the reaction is carried out in the presence of an effective amount of a polar aprotic organic solvent with a basicity such that it has a "donor number" below 25.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.