Detection and treatment of infections with immunoconjugates
US5332567A · kind A · utility
151Cited by
2References
29Claims
0Family size
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Inventor
Key dates
| Filing date | Mar 22, 1993 |
| Grant date | Jul 26, 1994 |
| Priority date | — |
| Expiry date | Mar 22, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of targeting a diagnostic or therapeutic agent to a focus of infection comprises injecting a patient infected with a pathogen parenterally with an antibody conjugate which specifically binds to an accessible epitope of the pathogen or of a pathogen-associated antigen accreted at the focus of infection, the antibody conjugate further comprising a bound diagnostic or therapeutic agent for detecting, imaging or treating the infection. Polyspecific composite conjugates enhance the efficacy of the method, which is especially useful for treating infections that are refractory towards systemic chemotherapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.