1,2-dihydro-2-oxopyridines

US5332750A · kind A · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Werner Mederski · Zwingenberg, DE
• Norbert Beier · Reinheim, DE
• Pierre Schelling · Mühltal, DE
• Ingeborg Lues · Darmstadt, DE
• Klaus-Otto Minck · Ober-Ramstadt, DE

Key dates

• Filing date: Apr 22, 1993
• Grant date: Jul 26, 1994
• Expiry date: Apr 22, 2013

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New 1,2-dihydro-2-oxopyridines of formula I ##STR1## in which R is the radical ##STR2## and R.sup.1 to R.sup.6 and X are as defined herein, and their salts, have antagonistic properties towards angiotensin II and can be used for the treatment of hypertension, aldosteronism and cardiac insufficiency.