Nitrofurantoin crystals
US5332832A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 11, 1992 |
| Grant date | Jul 26, 1994 |
| Priority date | — |
| Expiry date | Aug 11, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Nitrofurantoin particulates comprising discrete particulates of nitrofurantoin wherein: PA1 (a) said particulates are larger than about 200 mesh size; and PA1 (b) the BET surface area of said particulates is at least about 0.2 M.sup.2 /g. Preferably, the surface of said particulates consists essentially of nitrofurantoin monohydrate. Also preferably, said particulates comprise at least about 5%, more preferably at least about 50% of nitrofurantoin monohydrate. Preferred compositions of this invention comprise these nitrofurantoin particulates in an aqueous suspension. The nitrofurantoin particulates of this invention are highly efficacious for the delivery of nitrofurantoin in oral dosage forms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.