Microparticles as ultrasonic contrast media
US5333613A · kind A · utility
36Cited by
6References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 23, 1993 |
| Grant date | Aug 2, 1994 |
| Priority date | — |
| Expiry date | Mar 23, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/223
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Ultrasonic contrast media are provided comprising small particles with entrapped gas, where the compositions can be selected for rapid dissolution with production of microbubbles or maintaining the gas in microtubules, microchambers or microcracks, providing for echogenicity. The particles are readily formed by precipitation from a liquid, either solution or melt, of a monomeric material, followed by drying and mechanically reducing the size of the particles.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.