Process for biological production of amides with R. rhodochrous J-1
US5334519A · kind A · utility
27Cited by
2References
9Claims
0Family size
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Key dates
| Filing date | Oct 15, 1991 |
| Grant date | Aug 2, 1994 |
| Priority date | — |
| Expiry date | Oct 15, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08J2325/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
In a process for biological production of an amide wherein a nitrile is hydrated into a corresponding amide by the action of a nitrile hydratase originated in a microorganism, the improvement which comprises the use of nitrile hydratase which is obtained by culturing a microorganism of the species Rhodococcus rhodochrous in the presence of a cobalt ion. Aromatic nitriles such as a cyanopyridine as well as aliphatic nitrile such as acrylonitrile are hydrated into the corresponding amides.
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