Six-membered ring fused imidazoles substituted with phenoxyphenylacetic acid derivatives
US5334598A · kind A · utility
70Cited by
5References
8Claims
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Key dates
| Filing date | Mar 19, 1993 |
| Grant date | Aug 2, 1994 |
| Priority date | — |
| Expiry date | Mar 19, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Phenoxyphenylacetic acids and derivatives of general structural formula I have endothelin ##STR1## antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, congestive heart failure, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, inflammatory diseases, Raynaud's disease, and endotoxic shock, and asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.