Patent · US Expired

Glycoprotein isolated from ganoderma having immunosuppressive activity

US5334704A · kind A · utility

15Cited by
0References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 28, 1988
Grant dateAug 2, 1994
Priority date
Expiry dateApr 28, 2008

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/823
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed herein is a novel glycoprotein derived from Ganoderma mycelia. The glycoprotein is free of human hemagglutination ability, and has immunosuppressive activities and a molecular weight of 16,000-18,000 as measured by SDS gel electrophoresis or 12,000-16,000 as measured by tricin-SDS gel electrophoresis. The glycoprotein is produced by culturing Ganoderma mycelia, extracting the resultant Ganoderma mycelia with an aqueous solvent, and then purifying the resultant extract. An immunosuppressive agent containing an effective amount of the glycoprotein is also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.