Cyclophosphamide monohydrate and lactose
US5336669A · kind A · utility
10Cited by
3References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 20, 1993 |
| Grant date | Aug 9, 1994 |
| Priority date | — |
| Expiry date | May 20, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/675
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A parmaceutical preparation consisting essentially of a lyophilized cake of cyclophosphamide monohydrate and lactose prepared by the process of freezing cyclophosphamide, lactose and water, lyophilizing part of the water, obtaining and melting a supersaturated cyclophosphamide-lactose solution, precipitating cyclophosphamide as a hydrated polymorph, refreezing the solution and lyophilizing the water not bound to cyclophosphamide or lactose.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.