Oxidation products of cephalomannine
US5336684A · kind A · utility
17Cited by
8References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 26, 1993 |
| Grant date | Aug 9, 1994 |
| Priority date | — |
| Expiry date | Apr 26, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D305/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antineoplastic taxol derivatives are derived by selective oxidation of the alkene portion of the side chain of cephalomannine. The derivative displays high activity in promoting assembly of microtubulin and also displays cytotoxic activity against malignant cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.