Patent · US Expired

Thimerosal inactivated mycoplasma hyopneumoniae vaccine

US5338543A · kind A · utility

33Cited by
10References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 29, 1992
Grant dateAug 16, 1994
Priority date
Expiry dateMay 29, 2012

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/87
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to a method for making an inactivated vaccine of Mycoplasma hyopneumoniae by inactivating the bacteria with Thimerosal. The resulting bacterin is mixed with an adjuvant of aluminum hydroxide and DEAE dextran and injected into pigs. The resulting bacterin and adjuvant mixture can also be mixed with other bacteria such as Borderella and Pasteurella, for further adjuvant effect. Protective immunity against mycoplasmal pneumonia is elicited in swine using these vaccines.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.