Vaccinia virus containing DNA sequences encoding herpesvirus glycoproteins
US5338683A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Apr 4, 1990 |
| Grant date | Aug 16, 1994 |
| Priority date | — |
| Expiry date | Apr 4, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/20022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
What is described is a recombinant poxvirus, such as vaccinia virus, fowlpox virus and canarypox virus, containing foreign DNA from herpesvirus. In one embodiment, the foreign DNA is expressed in a host by the production of a herpesvirus glycoprotein. In another embodiment, the foreign DNA is expressed in a host by the production of at least two, particularly two or three, herpesvirus glycoproteins. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine. By the present invention, the barrier of maternal immunity in a newborn offspring can be overcome or avoided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.