Ultrapure human interleukin-6
US5338834A · kind A · utility
7Cited by
0References
10Claims
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Assignee
Inventor
Key dates
| Filing date | Jan 26, 1993 |
| Grant date | Aug 16, 1994 |
| Priority date | — |
| Expiry date | Jan 26, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Essentially pure human interleukin-6 having a purity of at least 98 % as determined by single peak migration using capillary electrophoresis is obtained by a 3-step purification method which includes a cation-exchange chromatography step, a hydrophobic chromatography step and a reverse-phase chromatography step in the presence of a charge modifier.
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