Process for preparing alpha-amino-phenylacetic acid-trifluoromethane sulfonic acid mixed anhydrides
US5338868A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 24, 1991 |
| Grant date | Aug 16, 1994 |
| Priority date | — |
| Expiry date | May 24, 2011 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C309/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is disclosed for the preparation of a compound of the Formula (VI) ##STR1## wherein X is a hydrogen atom, or OH, PA1 Y is a hydrogen atom, OH or a methyl group, PA1 R.sup.2 is a CH--COOR group, or a group of the formula (XI) ##STR2## and R is a C.sub.1 to C.sub.2 alkyl group, which comprises the step of: reacting a condensed salt of the Formula (IV) ##STR3## wherein Me is Na.sup.+ or K.sup.+, with a reactive derivative of trifluoromethane-sulfonic acid of the Formula (V) EQU F.sub.3 C--SO.sub.2 OH. The compounds of the Formula (VI) are intermediates in the preparation of penicillins and cephalosporins with antibiotic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.