Patent · US Expired

Peptide medicaments for the treatment of disease

US5340800A · kind A · utility

49Cited by
1References
9Claims
0Family size

Inventors

Key dates

Filing dateSep 9, 1992
Grant dateAug 23, 1994
Priority date
Expiry dateSep 9, 2012

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Peptide medicaments, and antibody thereto, useful for treating or preventing diseases, particularly diseases involving an inflammatory response by a host organism against infection, that are preferably derived from the .beta. subunit, CD18, of the leukocyte integrins, and that have the property of either interfering with, or preventing undesirable leukocyte adhesion to biological materials, particular to endothelial cells, or that interfere with, or prevent the chemotaxis of leukocytes through the endothelial cell monolayer, consequently minimizing undesirable cell/tissue leukocyte binding and thus preventing or minimizing diseases resulting therefrom.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.