Phenylcarboxamide compounds which have useful pharmaceutical activity
US5340827A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 14, 1993 |
| Grant date | Aug 23, 1994 |
| Priority date | — |
| Expiry date | Jun 14, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
##STR1## Compounds of formula (1) are described wherein Y represents a halogen atom or a group --OR.sup.1 where R.sup.1 represents an optionally substituted alkyl group; R.sup.2 represents an optionally substituted cycloalkylcycloalkenyl or polycycloalkyl group; R.sup.3 represents a hydrogen atom or an alkyl, aryl or aralkyl group; R.sup.4 represents an aryl or heteroaryl group; X represents --O--, --S--, --CH.sub.2 -- or --N(R.sup.5)--, where R.sup.5 is a hydrogen atom or an alkyl group; n is zero or an integer or value 1, 2 or 3; and the salts, solvates and hydrates thereof. The compounds are selective phosphodiesterase IV inhibitors and are useful for the prophylaxis or treatment of inflammatory diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.