Composition and method for treatment of vaginal yeast infections
US5340836A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 1, 1992 |
| Grant date | Aug 23, 1994 |
| Priority date | — |
| Expiry date | Jun 1, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/225
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition for the treatment of vaginal yeast which promotes normal vaginal bacterial growth during treatment, comprising a yeast-inhibitory agent selected from one or more of the group consisting of ethylene glycol, propylene glycol, and glycerol, and an effectively buffered aqueous acetate solution, in which the concentration of acetate is effective to establish a pH of the composition in the range of from about 5 to about 7, the presence of unionized acetate inhibits yeast selectively compared to the bacteria, and the proportions of the yeast-inhibitory agent and the buffering solution are effective to allow the active yeast-inhibitory agent to inhibit the vaginal yeast Candida. A method of treatment of vaginal yeast while promoting normal vaginal bacterial growth, by intravaginal application of the composition described above, is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.