Patent · US Expired

.GAMMA., .delta.T cell receptor and methods and detection

US5340921A · kind A · utility

6Cited by
1References
40Claims
0Family size

Assignees

Inventors

Key dates

Filing dateFeb 19, 1987
Grant dateAug 23, 1994
Priority date
Expiry dateFeb 19, 2007

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/868
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention provides purified polypeptides which comprise at least a portion of a .delta.T cell receptor polypeptide, a .gamma.T cell receptor polypeptide, a .gamma., .delta.T cell receptor complex or a .gamma., .gamma.T cell receptor complex. Substances capable of forming complexes with these polypeptides are also provided. Additionally, methods for detecting T cells which have within them or on their surfaces a polypeptide of the present invention are provided. Moreover, methods for diagnosing immune system abnormalities are provided which comprise measuring in a sample from a subject the number of T cells which have within them or on their surfaces a polypeptide of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.