Complexes possessing ortho ligating functionality
US5342604A · kind A · utility
28Cited by
10References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 17, 1992 |
| Grant date | Aug 30, 1994 |
| Priority date | — |
| Expiry date | Jun 17, 2012 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A group of functionalized amine chelants having ortho ligating functionality that form complexes with rare-earth type metal ions are disclosed. The chelants possess the general formula ##STR1## wherein R.sup.'1, R.sup.'2, R.sup.'3, R.sup.'4, R.sup.'5 and R.sup.'6, Z' and X are all defined in the specification. In addition certain of the chelant-radionuclide complexes can be effectively employed in compositions useful as therapeutic and/or diagnostic agents for calcific tumors and/or relief of bone pain.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.