Subdermal biocompatible implants
US5342622A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Oct 31, 1990 |
| Grant date | Aug 30, 1994 |
| Priority date | — |
| Expiry date | Oct 31, 2010 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0024
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides pharmaceutical or veterinary implants which, when subdermally administered releases a peptide or protein in a substantially continuous manner. The implant includes the peptide or protein and an excipient encased within a polymeric coating which is permeable, swellable and, at normal physiological pH, is non-rupturing, non-dissolving and does not degrade over the useful life the implant. The coating forms a release rate limiting barrier. All of the components used to make the implant are of a biocompatible nature. The implant is particularly useful for the sustained release of proteins or peptides for regulating the hormonally controlled reproductive cycle in sheep.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.