Imidazolidyl macrolides having immunosuppressive activity
US5344925A · kind A · utility
9Cited by
10References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 20, 1993 |
| Grant date | Sep 6, 1994 |
| Priority date | — |
| Expiry date | Sep 20, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Imidazolidyl macrolides of the general structural Formula I: ##STR1## have been prepared from suitable precursors by alkylation and/or arylation at C-3" and/or C-4" of the cyclohexyl ring. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases the prevention of rejection of foreign organ transplants and/or related afflictions, diseases and illnesses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.