Tetrahydrobenzimidazole derivatives and pharmaceutical compositions containing same
US5344927A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 30, 1993 |
| Grant date | Sep 6, 1994 |
| Priority date | — |
| Expiry date | Mar 30, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A tetrahydrobenzimidazole derivative represented by formula (I): ##STR1## wherein Het represents a heterocyclic group which may be substituted with 1 to 3 substituents selected from the group consisting of a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a cycloalkyl-lower alkyl group, an aralkyl group, a lower alkoxy group, a nitro group, a hydroxyl group, a lower alkoxycarbonyl group, and a halogen atom; and X represents a single bond or --NH-- which is bonded to the carbon atom or nitrogen atom of the heterocyclic ring, or a pharmaceutically acceptable salt thereof. The compound of formula (I) and a salt thereof exhibits antagonism against 5-HT.sub.3 receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.