Patent · US Expired

Phenothiazine derivatives, their production and use

US5344928A · kind A · utility

23Cited by
6References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 14, 1992
Grant dateSep 6, 1994
Priority date
Expiry dateApr 14, 2012

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/811
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

There is disclosed a novel phenothiazine derivative of the general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and are a C.sub.1-6 alkyl group and at least one of them has as a substituent a group which can react with amino group, thiol group or carboxyl group, and X.sup.- is a counter ion of the phenazathionium. Their production and the intermediates used in the production are also disclosed. The compound (I) is a derivative of methylene blue and is applicable to photodynamic therapy of cancer or immunoassays utilizing chemiluminescence.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.