Phenothiazine derivatives, their production and use
US5344928A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 14, 1992 |
| Grant date | Sep 6, 1994 |
| Priority date | — |
| Expiry date | Apr 14, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/811
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
There is disclosed a novel phenothiazine derivative of the general formula (I): ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and are a C.sub.1-6 alkyl group and at least one of them has as a substituent a group which can react with amino group, thiol group or carboxyl group, and X.sup.- is a counter ion of the phenazathionium. Their production and the intermediates used in the production are also disclosed. The compound (I) is a derivative of methylene blue and is applicable to photodynamic therapy of cancer or immunoassays utilizing chemiluminescence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.