Pharmaceutical compositions containing (65)-folinic acid and salts thereof
US5347005A · kind A · utility
10Cited by
4References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 2, 1992 |
| Grant date | Sep 13, 1994 |
| Priority date | — |
| Expiry date | Jun 2, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D475/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a process for preparing (6S)-folinic acid and its salts by recrystallization of alkaline-earth salts of (6R,S)-folinic acid and, where necessary, liberation of the acid from the alkaline-earth folinates and/or, where necessary, conversion into the alkali salts by at least one recrystallization in the presence of a base. The invention also relates to calcium-, magnesium-, potassium- and sodium-(6S)-folinates and to (6S)-folinic acid prepared in accordance with the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.