Tocotrienols in the treatment of hypercholesterolemia, hyperlipidemia and thromboembolic disorders
US5348974A · kind A · utility
25Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 10, 1993 |
| Grant date | Sep 20, 1994 |
| Priority date | — |
| Expiry date | Feb 10, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/72
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the use of tocotrienol, gamma-tocotrienol and delta-tocotrienol in reducing hypercholesterolemia, hyperlipidemia and thromboembolic disorders in mammals. The isolation of these tocotrienols from natural sources and their chemical synthesis is disclosed. The present invention also relates to prodrugs and pharmaceutical compositions of gamma-tocotrienol, delta-tocotrienol and tocotrienol and uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.