Process for pharmaceutical grade high purity hyodeoxycholic acid preparation
US5349074A · kind A · utility
3Cited by
4References
14Claims
0Family size
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Key dates
| Filing date | Jan 28, 1993 |
| Grant date | Sep 20, 1994 |
| Priority date | — |
| Expiry date | Jan 28, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J9/005
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process for pharmaceutical grade high purity hyodeoxycholic acid preparation starting from swine bile, consisting in the treatment of swine bile with sodium hydroxide, isolation of hyodeoxycholic, chenodeoxycholic and hyocholic acids by precipiation of their zinc salts and subsequent selective precipitation of the hyodeoxycholic acid magnesium salt, from which the acid is freed by acidification and then crystallized.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.