IBDV VP2 epitope recognized by virus neutralizing and protective monoclonal antibodies
US5350575A · kind A · utility
5Cited by
0References
17Claims
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Assignee
Inventors
Key dates
| Filing date | Apr 26, 1993 |
| Grant date | Sep 27, 1994 |
| Priority date | — |
| Expiry date | Apr 26, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2720/10022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A recombinant DNA molecule comprising a nucleotide sequence coding for a conformational epitope of the VP2 polypeptide of IBDV. In particular, a DNA molecule comprising a sequence which substantially corresponds to the AccI-SpeI fragment, and optionally the ScaI-XhoI fragment, of the IBDV genome segment coding for the VP2 polypeptide. Synthetic peptides or polypeptides, including fused polypeptides, prepared by expression of host cells containing these DNA molecules are also disclosed, as well as compositions for stimulating an immune response against IBDV comprising at least one such synthetic peptide or polypeptides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.