Patent · US Expired

Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis

US5350744A · kind A · utility

1Cited by
2References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 27, 1992
Grant dateSep 27, 1994
Priority date
Expiry dateAug 27, 2012

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D493/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds having the formula I: ##STR1## are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.