Patent · US Expired

Stabilized compositions containing non-glysylated human tissue type plasminogen activator derivative K2P pro

US5352452A · kind A · utility

5Cited by

7References

31Claims

0Family size

Assignee

Boehringer Mannheim GmbH · DE

Inventors

Ulrich Kohnert · Habach, DE
Rainer Rudolph · Waldshut-Tiengen, DE

Key dates

Filing date	Aug 2, 1991
Grant date	Oct 4, 1994
Priority date	—
Expiry date	Aug 2, 2011

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P7/02
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Stabilized compositions containing a non-glycosylated human tissue type plasminogen activator derivative are disclosed. The derivative is referred to as K2P pro. The composition has enzymatic activity of at least 1.1 mU/ml, a pH of from 4.5 to 6.5, and contains citrate as well as at least one of a variety of different compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.