Device for administering drug transdermally which provides an initial pulse of drug
US5352456A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 10, 1991 |
| Grant date | Oct 4, 1994 |
| Priority date | — |
| Expiry date | Oct 10, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2013/00906
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A transdermal drug delivery device that administers drug in an initial pulse followed by a substantially lower continuous rate comprising a drug reservoir of the drug dissolved in a carrier and a volatile permeation enhancer confined between a backing that is permeable to the volatile permeation enhancer and an underlying substrate layer that is permeable to the drug, carrier and enhancer. When the device is placed on the skin the volatile permeation enhancer is depleted from the reservoir by evaporation through the backing such that the magnitude and duration of the pulse is dependent upon the permeability of the backing layer to the volatile enhancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.