Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
US5352670A · kind A · utility
159Cited by
7References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 2, 1991 |
| Grant date | Oct 4, 1994 |
| Priority date | — |
| Expiry date | Oct 2, 2011 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed are methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides. Specifically, in the disclosed methods, sialyltransferase is activated to transfer an analogue of sialic acid, employed as its CMP-nucleotide derivative, to an oligosaccharide glycoside. The analogue of sialic acid and the oligosaccharide employed in this method are selected to be compatible with the sialyltransferase employed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.