Inhibitors of farnesyl protein transferase
US5352705A · kind A · utility
56Cited by
2References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 26, 1992 |
| Grant date | Oct 4, 1994 |
| Priority date | — |
| Expiry date | Jun 26, 2012 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/0606
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.