Poly(ethylene or propylene glycol)-containing polymer
US5352756A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jun 11, 1993 |
| Grant date | Oct 4, 1994 |
| Priority date | — |
| Expiry date | Jun 11, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08F290/062
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A crosslinked poly(ethylene or propylene)glycol-containing polymer which has a unique spatial structure and can be designed especially for application as a chromatographic resin or as a solid support for the synthesis of peptides, oligonucleotides or oligosaccharides or as a substrate for the immobilization of proteins. The polymer is formed by radical copolymerization of derivatized poly(ethylene or propylene) glycol bis-end substituted with a moiety selected from the group consisting of acryloylalkyl, acryloylaryl, acrylamidoalkyl and acrylamidoaryl with an acrylic amide, nitrile or ester. When it is to be used as a solid support or immobilization substrate, the polymer will incorporate a spacer comprising functional groups for the attachment of peptides, proteins, nucleotides or saccharides such as those selected from the group consisting of amino, alkylamino, hydroxy, carboxyl, mercapto, sulfeno, sulfino, sulfo and derivatives thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.