Oxidation process
US5352840A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 10, 1993 |
| Grant date | Oct 4, 1994 |
| Priority date | — |
| Expiry date | May 10, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C45/28
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Substituting aqueous hydrogen peroxide/hydrogen bromide for bromine in a known process for producing a ditertiaryalkyl substituted hydroxybenzaldehyde such as ditertiarybutyl hydroxybenzaldehyde from the corresponding ditertiaryalkyl substituted methylphenol results in a substantially impaired yield of product. Improved yields are obtained by employing a reaction temperature of at least 40.degree. C., preferably 50.degree. to 80.degree. C. in conjunction with a hydrophobic solvent such as chloroform. Preferably, the process employs very concentrated hydrogen peroxide solution, 65% to 75% w/w, introduced into the bromide-containing reaction mixture during a period of from 25 to 75 minutes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.